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Consistent eight-week vegan diet may help to reduce biological age

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A variety of lettuce at display. — Reuters/File

A recent study carried out by the Stanford Prevention Research Center and TruDiagnostic has revealed the effects an eight-week vegan diet versus an omnivorous diet can have on the biological age of a human body.

The researchers aimed to know how a short vegan diet would affect a human age and health compared to a non-vegan diet.

The results were drawn after assessing the blood DNA methylation and epigenetic aging and how the diet affected them.

The minds behind the research divided participants in two groups. The omnivorous group was assigned to eat protein and dairy like meat, eggs and milk while the other group was told to avoid all animal products.

Those who strictly complied with the vegan diet for eight weeks showed a decrease in the biological ages of five organs including the human heart, hormonal, liver, inflammatory and metabolic systems.

As for the omnivorous diet group, an increase was apparent in their tryptophan which is known to elevate serotonin levels indirectly helping in regulating moods.

Director of Bioinformatics at TruDiagnostic Varun Dwaraka, PhD told Medical News Today that, “these results were surprising, even among interventions using epigenetic tests.”

He further added that in other studies involving the epigenetic clocks, changes typically occur after three to six months; however, during this study, they observed massive changes in just eight weeks.

Raghav Sehgal who is a PhD candidate in Computational biology and Bioinformatics at Yale University, scientific advisor at TruDiagnostic, and Director of Bioinformatics at the Healthy Longevity Clinic also shared his remarks on the newest epigenetic study while talking to Medical News Today.

“When we look at multiple vegan diets and green Mediterranean (similar to vegan diets except for having milk in them) the common thread we see is that the epigenetic scores for inflammation, metabolic and musculoskeletal aging are all improving. In other words, these diets may be specifically targeting inflammatory and metabolic aging pathways via epigenetics in the body and slowing them down,” Sehgal explained.

“At the end of the day, the exact mechanism of how these diets are providing benefits might turn out to be through multiple different pathways in the body but the fact that they are providing benefits is very clear to us,” Sehgal concluded. 

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Pakistani conjoined twins successfully separated by Turkish doctors

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Pakistani conjoined twin girls, Mirha and Minal, separate after successful surgery by Turkish doctors at Bilkent City Hospital, Ankara. — Anadolu Agency

Turkish doctors successfully separated Pakistani twin girls, Mirha and Minal, who were conjoined at the skull after a marathon 14-hour surgery performed in two stages, according to state-run Anadolu news agency.

The surgery was conducted at Bilkent City Hospital, Ankara, after Turkish President Recep Tayyip Erdogan responded to the family’s plea for help as they were unable to find a suitable treatment in Pakistan.

After being contacted by renowned London-based pediatric neurosurgeon Owase Jeelani, Erdogan assured Jeelani that the babies’ treatment would be carried out in Turkey, as per Anadolu.

The 11-month-old twin girls travelled to the Turkish capital in May and were placed under close medical supervision.

The final 14-hour operation took place on July 19 by a surgical team led by Dr Jeelani along with Turkish physicians Dr Harun Demirci and Dr Hasan Murat Ergani.

Emphasising the extensive teamwork involved in the operation, the hospital’s head of the Department of Pediatric Hematology-Oncology Namik Yasar Ozbek told the Turkish news agency: “The babies had some issues with sitting and hand movements due to their conjoined state.”

“Post-surgery, our neurologists, physical therapists and neurodevelopmental specialists resolved these issues,” he added.

“The babies are now doing very well, starting to use their hands and arms, and gaining head control. In 10 days, they will celebrate their first birthdays separately,” Ozbek said.

“Seeing the babies healthy now is an incredible joy,” said Turkish physician Ergani, who was part of Dr Jeelani-led surgical team, adding: “When we successfully separated them, the entire medical team looked at each other and applauded. It was one of the most memorable moments of my life.”

Speaking to the news agency, the twins’ parents, Rehan Ali and Nazia Parveen, expressed their profound gratitude to President Erdogan, the medical team, and everyone involved in their children’s treatment.

“We are very happy and indebted to everyone who contributed,” said the father, adding that they hope to meet Erdogan to thank him personally.

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Pakistan’s mpox tally rises to 7 as another case reported

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Vials of the JYNNEOS smallpox and monkeypox vaccine are placed on a table during a clinic offered by the Pima County Department of Public Health at Abrams Public Health Centre in Tucson, Arizona, US, August 20, 2022. — Reuters

ISLAMABAD: A 44-year-old man, hailing from the Gujarat district in Punjab, has tested positive for monkeypox virus or mpox after arriving in Pakistan from a gulf state marking the seventh mpox case in the country this year and the sixth since the World Health Organisation (WHO) declared an emergency last month.

After being suspected of carrying the virus, the patient, who landed at Islamabad Airport on September 14 (Saturday), was taken to the Pakistan Institute of Medical Sciences (Pims).

The health officials confirmed that samples sent to the National Institute of Health (NIH) tested positive for mpox. The patient is reported to be in stable condition.

“This is the seventh confirmed case of mpox in Pakistan this year,” said a health official in the federal health ministry.

“Five previous cases were confirmed at the Khyber Medical University laboratory in Peshawar, while this latest patient is being treated in Islamabad,” the official said.

Mpox is a virus that causes flu-like symptoms and pus-filled lesions and, while usually mild, it can kill. Children, pregnant women and people with weakened immune systems are all at higher risk of complications.

Earlier on Wednesday, one more mpox case was reported in Khyber Pakhtunkhwa (KP), taking the total tally of the virus to six in Pakistan, provincial Health Minister Syed Qasim Ali Shah said

Moreover on Sunday, at least three passengers travelling to Karachi were suspected of monkeypox in a single day at the Jinnah International Airport, Geo News reported citing sources.

All three passengers returned to Pakistan from Middle Eastern countries, the sources added.

Following global health concerns, WHO has approved MVA-BN as the first pre-qualified vaccine against monkeypox virus, according to The News on Saturday.

“This first pre-qualification of a vaccine against mpox is an important step in our fight against the disease, both in the context of the current outbreaks in Africa and in future,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus.

The development comes as the United Nations’ health centric-body had declared the mpox outbreak as an “international health emergency” in July.

The spike in mpox cases in Peshawar has triggered concerns among health experts and the public alike, with calls for increased awareness and stricter travel guidelines.

Authorities continue to monitor the situation closely, particularly in light of the WHO’s recent emergency declaration regarding the virus, he added and lauded Border Health Services (BHS) to finally detect an mpox case other than Peshawar.

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Three possible mpox patients sent home as tests return negative

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A test tube labelled “Mpox virus positive” is held in this illustration taken August 20, 2024. — Reuters

Three suspected mpox patients were sent home in Karachi after one showed no symptoms and the tests for the other two came back negative, according to the Sindh health department.

Geo News, citing sources, reported on Sunday that they were suspected of being infected with mpox after returning to Pakistan from Middle Eastern countries at the Jinnah International Airport. 

The patient with no symptoms of the virus was sent home yesterday, the health department stated that the other two suspects, were also discharged from the hospital after testing negative. 

The two had arrived in Karachi from Jeddah on Saturday, according to the health department.

All three individuals were immediately taken to the Sindh Infectious Diseases Hospital and Research Centre, as confirmed by hospital officials.

Currently, there are six confirmed mpox cases in Pakistan, with the majority reported in Khyber Pakhtunkhwa.

Mpox is a virus that causes flu-like symptoms and pus-filled lesions and, while usually mild, it can kill. Children, pregnant women and people with weakened immune systems are all at higher risk of complications, reported Reuters.

The infectious disease has African countries in turmoil including DR Congo where there have been 27,000 cases and more than 1,100 deaths, the majority of the deaths occurred among children.

The outbreak began in January 2023 in the Congo and in August this year, the World Health Organisation (WHO) declared the recent outbreak of the disease a public health emergency of international concern after the new variant was identified.

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Authorities identify three suspected mpox patients at Karachi airport

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This file photo shows a patient showing his hand with a sore caused by an infection of the mpox virus. — AFP 

KARACHI: As Pakistan continues to report fresh monkeypox cases, three more passengers travelling to Karachi were suspected of the disease, sources told Geo News on Sunday. 

According to the sources, the three passengers, including a female, were returning to Pakistan from Middle Eastern countries and had landed at Karachi’s Jinnah International Airport. 

The suspected patients have been shifted to Sindh government’s Infectious Diseases Hospital, said the sources, adding that they will be kept in isolation ward until the test report comes.

The total tally of confirmed mpox cases is six across Pakistan with most cases reported in Khyber Pakhtunkhwa.

Mpox is a virus that causes flu-like symptoms and pus-filled lesions and, while usually mild, it can kill. Children, pregnant women and people with weakened immune systems are all at higher risk of complications, reported Reuters.

In August, the WHO The World Health Organisation declared the recent outbreak of the disease a public health emergency of international concern after the new variant was identified.

There have been 27,000 cases and more than 1,100 deaths, mainly among children, in DR Congo since the current outbreak began in January 2023.

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